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Karan Wadhwa PhD (Cantab), FRCS (Urol)

Karan was initially appointed as a Consultant Urological Surgeon at Chelmsford in 2019. Karan qualified from Nottingham University in 2006 and completed a PhD at the University of Cambridge in 2015.

Karan was initially appointed as a Consultant Urological Surgeon at Chelmsford in 2019. Karan qualified from Nottingham University in 2006 and completed a PhD at the University of Cambridge in 2015.

Karan originally qualified from the University of Nottingham in 2006 with a first class honours degree (Bachelor in Medical Science) alongside his medical qualification. He did his very early training the Nottinghamshire region before pursuing surgical training in the Southwest. Karan completed Urological training as a prestigious Academic Clinical Fellow in the East of England based out of Cambridge University. Here he obtained a very competitive grant with funding from Medical Research Council for his research on the detection of prostate cancer which led to the award of his PhD from the University of Cambridge. He has trained in a wide field of local hospitals including Addenbrookes, Ipswich and the Norfolk & Norwich Hospital.

Karan has multiple publications, has presented widely on range of urological topics at national and international conferences and meetings, and has won several prizes for his work. His key clinical interests include Robotic and laparoscopic surgery for kidney cancers and benign kidney and adrenal conditions as well as diagnostic urology, treatment of urological infections, surgery for prostatic enlargement, kidney stones and penoscrotal conditions.

He is the current Clinical Lead of the Department of Urology at Broomfield hospital and has led several innovative projects to improve patient outcomes. Karan is a passionate educator with Associate Fellowship of the Higher Education Academy. He is an Associate Clinical Lecturer with Anglia Ruskin University Medical School as a head of year and is involved in both lecturing and bedside teaching, as well as mentorship and examining several cohorts of medical students from Barts and the London as well as ARU in Chelmsford.

Karan is married to Deepa, a local optometrist, with two very young boys who take up most of his time! In any spare time he has, he likes to cook, enjoys keeping fit at the gym and is a keen petrolhead with a passion for cars and motorcycles.

Some of Karan's publications

Partial versus Radical Nephrectomy

Wadhwa K and Rochester M, BJUi Knowledge, Online publication accepted October 2018

Identification of potential therapeutic targets in prostate cancer through a cross-species approach

EMBO Mol Med. 2018 Feb 5. pii: e8274. doi: 10.15252/emmm.201708274. PMID:29437778

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer

Nat Commun. 2017 Aug 29;8(1):374. doi: 10.1038/s41467-017-00393-y. PMID:28851861.

Loss of hSef promotes metastasis through up-regulation of EMT in prostate cancer

Int J Cancer. 2017 Jan 10. doi: 10.1002/ijc.30604. PMID:28073170.

Robotic assisted laparoscopic radicalprostatectomy following transrectal compared to transperineal prostate biopsy: surgical, oncological and functional outcomes.

Minerva Urol Nefrol. 2017 Feb;69(1):85-92. doi: 10.23736/S0393-2249.16.02759-4. PMID: 28009149.

The role of prostatic urethral biopsies as a staging tool for bladder cancer

J. Clin Urol. 2016 Sept. DOI: 10.1177/2051415816671465.

The influence of environmental conditions on the incidence of renal colic in Rome

Urologia. 2016 May 24;83(2):77-82. doi: 10.5301/uro.5000170. PMID: 27103092

Magnetic Resonance and Ultrasound Image Fusion Supported Transperineal Prostate Biopsy Using the Ginsburg Protocol: Technique, Learning Points, and Biopsy Results

Eur Urol. 2016 Aug;70(2):332-40. doi: 10.1016/j.eururo.2016.02.064. PMID: 26995327.

Transperineal prostate biopsies for diagnosis of prostate cancer are well tolerated: a prospective study using patient-reported outcome measures

Asian J Androl. 2017 Jan-Feb;19(1):62-66. doi: 10.4103/1008-682X.173453. PMID: 26924279

Investigating the ability of multiparametric MRI to exclude significant prostate cancer prior to transperineal biopsy

Canadian Urology Association Journal 2015;9(11-12):E853-8.

Targeted transperineal biopsy of the prostate has limited additional benefit over background cores for larger MRI-identified tumors

World J Urol. 2015 Aug 4. PMID: 26238348.

The Post PSA era, new developments in prostate cancer diagnostics


Salt- inducible Kinase 2 Regulates Mitotic Progression and Transcription in Prostate Cancer

Mol Cancer Res. 2014 Dec 29. pii: molcanres.0182.2013

Defining the Learning Curve in the Implementation of multi-parametric MRI for image guided prostate biopsies

BJU Int. 2014 Aug 7. doi: 10.1111/bju.12892

Case that changed my practice: Revisiting the use of ileal conduit urodynamics

Journal Of Clinical Urology, 2014 Oct. doi: 10.1177/2051415814550841

Definitions of terms, processes and a minimum dataset for transperineal prostate biopsies: a standardization approach of the Ginsburg Study Group for Enhanced Prostate Diagnostics

BJU Int. 2013 Sep;112(5):568-77. doi: 10.1111/bju.1213

Live kidney donation: what are our ethical responsibilities?

TRENDS IN UROLOGY & MEN’S HEALTH Volume 4, Issue 2, March/April 2013, Pages: 25–28, DOI: 10.1002/tre.321

Prostatic Basal Cell Carcinoma: A Case Report And Review Of The Literature

Journal of Clinical Urology May 2011 vol. 4 no. 3 126-127 doi:.1016/j.bjmsu.2010.0

Bladder extramedullary plasmacytoma and synchronous bladder urothelial transitional cell carcinoma: A case report and review of the literature

Open Access J Urol. 2011 Feb 15;3:25-7. doi: 10.2147/OAJU.S10897.

Atypical development of Sertoli cells and impairment of spermatogenesis in the hypogonadal (hpg) mouse

Journal of Anatomy 207 (6), 797–811

Chapter 20: Renal Cancer, Diagnosis and Management in the Outpatient Clinic

First published: 12 January 2021